In our case, we had installed properly OOB patch for SharePoint 2019 July 19th, 2025 (KB5002754), Antimalware Scan Interface (AMSI) is turned on, an appropriate antivirus solution is in place (Windows Defender + EDR Block Mode with MDE), the ASP.NET machine keys was rotated after all changes. But we still receiving alerts about "SuspSignoutReq".
After diagnostic, we can observe AMSI was preventing the execution properly. It really happen something with our IIS w3wp.exe service. The flagged action is "POST request to /_layouts/15/ToolPane.aspx?DisplayMode=Edit" with header field referring to : /_layouts/SignOut.aspx
The reason is: not just antivirus solutions was improving our detection about this vulnerability, Other security tools too ! We use a VDR scan and this one try to exploit the breach. No real malicious attacker.
... But something tell me the vulnerability is not totally erased by this patch, just a mitigation. Microsoft seem to just added a signature to identify a malicious action and prevent the action ! This will not stop to receive alerts when someone knock at door... may be generate more alerts (even if the action was prevented).