If Microsoft Defender Antivirus and Defender Offline cannot find any threats or finds but cannot remove threats, there are various secondary opinion scanners which can be used to supplement your existing antivirus.
- Emsisoft Emergency Kit (EEK)
- Malwarebytes Anti-Malware
- Sophos Scan & Clean
- Microsoft Safety Scanner (MSERT) 32-bit or 64-bit
I provide a more detailed list of malware removal tools with scanning instructions in Supplementing your Anti-Virus Program with Anti-Malware Tools (Post #4)...just scroll down near the bottom of that post.