Hi @Gwendolyn Denton
Thank you for posting your question in the Microsoft Q&A forum.
It seems like the 500 error you're encountering occurs is typically caused by incomplete bot configuration within Azure. For Copilot in Teams to function correctly, the bot must be enabled not only for the standard channels but also for the Microsoft 365 channel. We've received similar reports from other users recently, and the product team has acknowledged this as a known issue that is currently under investigation.
In the meantime, I recommend reviewing this guide to see if enabling the Microsoft 365 channel helps in your tenant: Extend Message Extension to Outlook - Teams | Microsoft Learn.
If the issue persists after making that adjustment, please submit a support request to the Azure Support team. Since this appears to be related to Azure-specific configuration, their team has the appropriate tools and access to investigate the matter further. While we’re here to guide you as much as possible, our capabilities as forum moderators are limited when it comes to deeper technical troubleshooting.
If you need help submitting a support request, this article walks you through the process: How to create an Azure support request - Azure supportability | Microsoft Learn
Thank you for your patience and understanding.
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